Human Sera
Cayman Chemical ClofentezIn 50mg
An acaricide; has broad-spectrum activity against various plant-feeding mite species; lethal to wild-type, but not chs1 mutant, T. urticae mite eggs (LC50s = 1.2 and >5,000 mg/L, respectively); induces formation of thyroid tumors in male rats from 13-1,000 mg/kg per day
Cayman Chemical 2-ThIourIdIn 50mg
A modified nucleobase found in tRNAs that is known to stabilize U:A pairs
Cayman Chemical Betamethason 50mg
A synthetic corticosteroid; reduces BALF MMP-2 and MMP-9 activities, TNF-α levels, and neutrophil number in a mouse model of LPS-induced lung injury; prenatal administration improves neonatal lung function but decreases hippocampal and corpus callosum neuron density and induces motor function deficits in a rabbit model of late preterm birth at 0.1 mg/kg; extends gestational length in a rat model of HMGB1-induced preterm labor
Cayman Chemical FlavoxatehydrochlorIde 50mg
An inhibitor of L-type calcium channels and an antimuscarinic agent; induces relaxation of potassium-precontracted isolated human urinary bladder detrusor muscle (IC50 = 2 µM) and reduces carbachol- or calcium-induced contractions in isolated rat detrusor strips; inhibits reflex micturition in decerebrated cats when microinjected into the oral pontine reticular nucleus at 0.68 UG/animal
Cayman Chemical DracorhodIn Perchlorate 100mg
A pro-apoptotic compound and a synthetic analog of dracorhodin; cytotoxic to U937, A375-S2, and MCF-7 cells in a concentration-dependent manner; cytotoxic to HeLa cells, an effect that can be reversed by Ac-YVAD-CMK, A-DEVD-FMK, Z-IETD-FMK, and Z-LEHD-FMK, which are inhibitors of caspase-1, -3, -8, and -9, respectively
Cayman Chemical nIdulafungIn 50mg
A semisynthetic echinocandin antifungal; inhibits 1,3-β-D glucan synthase from several C. albicans clinical isolates (IC50s = 0.89-7.96 ng/ml for the wild-type enzyme); active against C. albicans, C. parapsilosis, C. tropicalis, and C. guiillermondi (MICs = ≤0.03-4 UG/ml) and A. fumigatus (MIC90 = ≤0.03 UG/ml); increases survival and decreases the severity of pulmonary lesions in A. fumigatus-infected neutropenic rabbits at 10 mg/kg
Cayman Chemical DMnose6PhosphATsodIum 100mg
A phosphorylated aldohexose that can be used to produce glucose, mannitol, or N-glycans; also a ligand for both cation-dependent and -independent receptors and binds, as part of an N-glycan, to MRH domains on other proteins
Cayman Chemical OleIc nhydrIde 50mg
A fatty acid anhydride; inhibits sphingosine-induced phosphorylation of p32 in Jurkat T cells from 30-100 μM; has been used in the synthesis of various phospholipids and triglycerides
Cayman Chemical TalnIflumate 50mg
A prodrug form of niflumic acid; decreases the rate of chloride/bicarbonate exchange in isolated mouse intestinal villous epithelial cells at 100 µM; dietary administration increases survival but has no effect on the number of crypt goblet cells in the jejunum or cecum in a cystic fibrosis mouse model of distal intestinal obstructive syndrome at 88 mg/kg
Cayman Chemical BenocyclIdIn 50mg
A derivative of phencyclidine that acts as a potent and selective dopamine reuptake inhibitor (IC50 = 8 nM); intended for forensic and research applications
Cayman Chemical NBenzylACTAmIdInhydrobro 100mg
A potent inhibitor of iNOS (IC50 = 0.20 μM), with over 1,000-fold selectivity compared to eNOS (IC50 = 350 μM)
Cayman Chemical CnabIgerol 50mg
An analytical reference standard categorized as a phytocannabinoid; intended for research and forensic applications
Cayman Chemical N2Isobutyryl5O 4 4dIme 100mg
A building block; has been used in the synthesis of oligodeoxyribonucleotides
Cayman Chemical DerythroLthreo Lysosphngo 50mg
A mixture of the bioactive sphingolipids D-erythro and L-threo lysosphingomyelin
Cayman Chemical -CnabIchromen 50mg
An analytical reference standard categorized as a phytocannabinoid; induces catalepsy, hypothermia, hypolocomotion, and antinociception in the mouse tetrad assay for cannabimimetic activity; intended for research and forensic applications